Plants as Bioreactors- A Review
نویسندگان
چکیده
منابع مشابه
Plants as Bioreactors- A Review
Ever since the discovery of genetic manipulation and the establishment of various methods for effective transformation of cells, the use of plants as an expression system for the production of recombinant therapeutic proteins have been advocated. This has been an exciting as well as controversial concept. Plants produce large biomass hence plants can produce large quantities of recombinant prot...
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Recent advances in molecular and cellular biology have led to the development of technology to engineer plants that are capable of producing a wide variety of products. These include products for pharmaceutical applications, like vaccine antigens, antibodies, antibody-derived fragments and other therapeutic proteins. It is possible to alter endogenous metabolic pathways to obtain new products, ...
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Plants have been identified as promising expression systems for commercial production of vaccine antigens. In phase I clinical trials several plant-derived vaccine antigens have been found to be safe and induce sufficiently high immune response. Thus, transgenic plants, including edible plant parts are suggested as excellent alternatives for the production of vaccines and economic scale-up thro...
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Plants are emerging as a promising alternative to conventional platforms for the large-scale production of recombinant proteins. This field of research, known as molecular farming, is developing rapidly and several plant-derived recombinant proteins are already in advanced clinical trials. However, the full potential of molecular farming can only be realized if we gain a fundamental understandi...
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ژورنال
عنوان ژورنال: Advanced Techniques in Biology & Medicine
سال: 2015
ISSN: 2379-1764
DOI: 10.4172/2379-1764.1000161